Genetic Diversity of the Antiviral Mx Gene in 14 Chicken Lines

  • Patricia Davison (National Science Foundation Research Experience for Undergraduates)
  • Michael G. Kaiser (Iowa State University)
  • Susan J. Lamont (Iowa State University)
  • Charles F. Curtiss (Iowa State University)


Genetic resistance to avian influenza has previously been associated with a Ser631Asn mutation of the chicken Mx gene. A portion of the Mx gene from 14 genetically diverse chickens lines were PCR amplified and sequenced. The Ser631Asn mutation showed genetic variation among the Iowa State University chicken lines, with some lines having the resistant allele while other lines had the susceptible allele. The diversity in the Mx gene warrants future studies into contrasting host resistance after viral infection in these Iowa State University lines.

Keywords: ASL R2330

How to Cite:

Davison, P., Kaiser, M. G., Lamont, S. J. & Curtiss, C. F., (2008) “Genetic Diversity of the Antiviral Mx Gene in 14 Chicken Lines”, Iowa State University Animal Industry Report 5(1). doi: https://doi.org/10.31274/ans_air-180814-766

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Published on
01 Jan 2008
Peer Reviewed