Poultry

More MHC-like Class I Y mRNA Detected in Relatively Resistant Fayoumis than Susceptible Leghorns

Authors
  • Melissa S. Deist (Iowa State University)
  • Rodrigo A. Gallardo (University of California, Davis)
  • David A. Bunn (University of California, Davis)
  • Terra R. Kelly (University of California, Davis)
  • Jack C. M. Dekkers (Iowa State University)
  • Huaijun Zhou (University of California, Davis)
  • Susan J. Lamont (Iowa State University)

Abstract

The inbred chicken lines Fayoumi and Leghorn have been shown to be relatively resistant and susceptible, respectively, to Newcastle disease virus (NDV). In this experiment we detected higher gene expression levels of MHC-like class I Y (MHCIY) in the Fayoumi trachea, lung, and Harderian gland of NDV challenged and nonchallenged birds across multiple time points. MHC region is important to the immune system and is often associated with resistance to pathogens. This gene may be associated with the Fayoumis’ resistant phenotype.

How to Cite:

Deist, M. S., Gallardo, R. A., Bunn, D. A., Kelly, T. R., Dekkers, J. C., Zhou, H. & Lamont, S. J., (2018) “More MHC-like Class I Y mRNA Detected in Relatively Resistant Fayoumis than Susceptible Leghorns”, Iowa State University Animal Industry Report 15(1). doi: https://doi.org/10.31274/ans_air-180814-315

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Published on
01 Jan 2018
Peer Reviewed