Early Inflammation Disorder in Neonatal Calves

  • Lucas A. Krueger (Iowa State University)
  • Donald C. Beitz (Iowa State University)
  • Robert L. Stuart (Stuart Products, Inc.)
  • Judith R. Stabel (Iowa State University)


In the present study, 30 Holstein calves were acquired at birth and were randomly subjected to one of six treatments. One treatment group was colostrum deprived (CD) and five other treatment groups were fed colostrum replacer (CR). Of the five CR groups, one group was not further supplemented (CR), one received vitamin A (CR-A), one received vitamin D (CR-D), one received vitamin E (CR-E), and one received vitamins A, D, and E (CR-ADE). Additionally, all calves were inoculated with Mycobacterium avium, subsp. paratuberculosis on d 1 and d 3 of age. One d after birth, CD calves exhibited lower IgG1, haptoglobin, and serum amyloid A concentrations in serum compared with the other five CR groups. These findings point to an endogenous early inflammation disorder in calves that are not fed colostrum.

Keywords: ASL R2969, Animal Science, Veterinary Microbiology and Preventive Medicine

How to Cite:

Krueger, L. A., Beitz, D. C., Stuart, R. L. & Stabel, J. R., (2015) “Early Inflammation Disorder in Neonatal Calves”, Iowa State University Animal Industry Report 12(1). doi: https://doi.org/10.31274/ans_air-180814-1290

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Published on
01 Jan 2015
Peer Reviewed