Baseline Immune Cell Composition in Broiler Spleen is Altered by Probiotic Supplementation

  • Krysten Fries-Craft (Iowa State University)
  • Meaghan Meyer (Iowa State University)
  • Elizabeth Bobeck (Iowa State University)


Probiotics are supplemented in poultry diets to support beneficial intestinal microbial community members. The alteration of the microbiota due to probiotic supplementation is shown to improve host health, but the underlying changes to immune cell populations have not been well-described in poultry. The objective of this study was to examine the effects of probiotics at two different dietary inclusion levels on the immune cell populations in spleens of unchallenged broiler chickens. Probiotic supplementation did not impact overall percentages of leukocytes, but did alter the composition of cells making up leukocyte subpopulations (P ≤ 0.05). Additional research is needed to evaluate how these changes to immune cell populations translate to a modulated immune response under challenge conditions.

Keywords: Probiotics, Immmunity, Broiler

How to Cite:

Fries-Craft, K. & Meyer, M. & Bobeck, E., (2021) “Baseline Immune Cell Composition in Broiler Spleen is Altered by Probiotic Supplementation”, Iowa State University Animal Industry Report 17(1). doi: https://doi.org/10.31274/air.11540

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Published on
25 Jan 2021