Breeding Physiology

Genetic and Physical Mapping of the pig Vascular Cell Adhesion Molecule 1 (VCAM1) gene to pig chromosome 4

Authors: Christopher K. Tuggle (Iowa State University) , Tun-Ping Yu (Iowa State University) , Hsiao-Fang Sun (Iowa State University) , Lizhen Wang (Iowa State University) , Max F. Rothschild (Iowa State University) , M. Yerle (Institut National de la Recherche Agronomique)

Abstract

We have developed methods to identify genetic differences at the VCAM1 gene in pigs. We identified significant variability in Chinese and American breeds, with three different forms of this gene and five of the six possible resulting genotypes seen in Duroc and Landrace breeds. This variability was used to map the VCAM1 gene to pig chromosome 4, a chromosome with important quantitative trait loci. We also used our methods to physically map VCAM1 to the end of the long arm of chromosome 4, confirming the genetic linkage assignment.

Keywords: ASL R1378

How to Cite: Tuggle, C. K. , Yu, T. , Sun, H. , Wang, L. , Rothschild, M. F. & Yerle, M. (1997) “Genetic and Physical Mapping of the pig Vascular Cell Adhesion Molecule 1 (VCAM1) gene to pig chromosome 4”, Iowa State University Animal Industry Report. 1(1).