Poultry

Response of Chicken-Originated Cells to Virus Mimic

Authors: Susan J. Lamont (Iowa State University) , Hyun-Jun Jang (Chonbok National Museum)

Abstract

We successfully cultured fibroblast cells and bone marrow-derived cells from White Leghorn and Fayoumi breed chickens. Treatment with a viral-mimic molecule demonstrated breed and cell-type specific differences in cell survival. Thus, we established a cell-based assay system that may be further explored as a substitute for challenging live animals with viruses to determine factors influencing their response. This could form a cost-effective and welfare-friendly method to determine viral responses.

Keywords:

How to Cite: Lamont, S. J. & Jang, H. (2019) “Response of Chicken-Originated Cells to Virus Mimic”, Iowa State University Animal Industry Report. 16(1).