Animal Health

SNPs in Region of NF-Kappa-B Gene Associated with Expression of Immune-Related Genes

Authors: Erin Sandford (Iowa State University) , Ceren Ciraci (Iowa State University) , Behnam Abasht (Iowa State University) , Jack C.M. Dekkers (Iowa State University) , Susan J. Lamont (Iowa State University)

Abstract

Selection to enhance immune response is difficult. Gene expression was assessed in two advanced intercross lines of chickens for various immune-related genes. Single nucleotide polymorphisms, SNPs, were identified in regions local to each gene and around a distant transcription factor, NF-Kappa-B, NFKB. These SNPs were used to identify expression QTL, eQTL, to aid in selection of immune gene expression. These eQTL may provide effective resources to which marker assisted selection may be applied.

Keywords: ASL R2483

How to Cite: Sandford, E. , Ciraci, C. , Abasht, B. , Dekkers, J. C. & Lamont, S. J. (2010) “SNPs in Region of NF-Kappa-B Gene Associated with Expression of Immune-Related Genes”, Iowa State University Animal Industry Report. 7(1). doi: https://doi.org/10.31274/ans_air-180814-95