Animal Health

Passive Immunization of Piglets Using Equine Plasma Containing PRRS Virus-Neutralizing Antibodies

Authors
  • Mark Mogler (Iowa State University)
  • D.L. Hank Harris (Iowa State University)

Abstract

Horses were inoculated with several strains of virulent PRRS virus. Sera from the horses were tested for the presence of PRRS virus-neutralizing antibodies.

Large volumes of equine plasma were collected and used to passively immunize piglets. Sera were collected at various time points after immunization and tested for virus-neutralizing activity.

These results show that horses are capable of generating high neutralizing antibody titers to PRRSV when exposed to virulent virus. Piglets develop neutralizing antibody titers to PRRSV when passively immunized with a sufficient volume of ά-PRRSV equine plasma.

Keywords: ASL R2255

How to Cite:

Mogler, M. & Harris, D. H., (2008) “Passive Immunization of Piglets Using Equine Plasma Containing PRRS Virus-Neutralizing Antibodies”, Iowa State University Animal Industry Report 5(1). doi: https://doi.org/10.31274/ans_air-180814-171

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Published on
01 Jan 2008
Peer Reviewed