Development of an Alphavirus Replicon Classical Swine Fever Virus Vaccine Candidate

J. Dustin Loy; Mark Mogler; Jill Gander; Kurt I. Kamrud; D.L. Hank Harris

doi:10.31274/ans_air-180814-1256

Animal Health

Development of an Alphavirus Replicon Classical Swine Fever Virus Vaccine Candidate

Authors: J. Dustin Loy (Iowa State University) , Mark Mogler (Iowa State University) , Jill Gander (Harrisvaccines, Inc.) , Kurt I. Kamrud (Iowa State University) , D.L. Hank Harris (Iowa State University)

Abstract

Classical swine fever virus (CSFV) E2 glycoprotein was expressed in an alphavirus based replicon expression system. Vaccinated pigs developed CSFV-specific antibodies. This is the first known use of this technology against CSFV.

Keywords: ASL R2752

How to Cite: Loy, J. , Mogler, M. , Gander, J. , Kamrud, K. I. & Harris, D. H. (2013) “Development of an Alphavirus Replicon Classical Swine Fever Virus Vaccine Candidate”, Iowa State University Animal Industry Report. 10(1). doi: https://doi.org/10.31274/ans_air-180814-1256