Animal Health

Expression and Immunogenicity of an Alphavirus Replicon African Swine Fever Virus Vaccine Candidate in Swine

Authors: Mark Mogler (Iowa State University) , Kurt I. Kamrud (Iowa State University) , Jill Gander (Harrisvaccines, Inc.) , D.L. Hank Harris (Iowa State University)

Abstract

African swine fever virus (ASFV) proteins were expressed in an alphavirus based replicon expression system. Pigs vaccinated with the recombinant vectors developed ASFV-specific antibodies. This is the first known use of this technology against ASFV.

Keywords: ASL R2751

How to Cite: Mogler, M. , Kamrud, K. I. , Gander, J. & Harris, D. H. (2013) “Expression and Immunogenicity of an Alphavirus Replicon African Swine Fever Virus Vaccine Candidate in Swine”, Iowa State University Animal Industry Report. 10(1). doi: https://doi.org/10.31274/ans_air-180814-861