Unique Genetic Differences in Responses of Chicken Immune Cells to an Inflammatory Stimulus and Heat Stress

Angelica G. Van Goor; Anna Slawinska; Carl Schmidt; Susan J. Lamont

doi:10.31274/ans_air-180814-229

Poultry

Unique Genetic Differences in Responses of Chicken Immune Cells to an Inflammatory Stimulus and Heat Stress

Authors: Angelica G. Van Goor (Iowa State University) , Anna Slawinska (UTP University of Science and Technology in Bydgoszcz) , Carl Schmidt (University of Delaware) , Susan J. Lamont (Iowa State University)

Abstract

Bone marrow antigen presenting cells (BM-APC), from Fayoumis (disease resistant and heat tolerant) and Leghorn (disease susceptible) chicken lines were evaluated for response to an inflammatory stimulus and heat stress. BM-APC from Fayoumis produced more nitric oxide (NO) and had higher Major Histocompatibility Complex (MHC) class II cell surface expression compared to those from Leghorn, indicating that BM-APC studied in vitro may be a useful tool to evaluate molecular effects of disease and/or heat tolerance in chickens.

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How to Cite: Van Goor, A. G. , Slawinska, A. , Schmidt, C. & Lamont, S. J. (2016) “Unique Genetic Differences in Responses of Chicken Immune Cells to an Inflammatory Stimulus and Heat Stress”, Iowa State University Animal Industry Report. 13(1). doi: https://doi.org/10.31274/ans_air-180814-229