Exposure to Heat Stress and anImmune Stimulus AffectsGene Expression in Chicken Immune Tissues
- Melissa S. Monson (Iowa State University)
- Angelica G. Van Goor (Iowa State University)
- Christopher M. Ashwell (North Carolina State University)
- Michael E. Persia (Virgnia Polytechnic Institute and State University)
- Max F. Rothschild (Iowa State University)
- Carl J. Schmidt (University of Delaware)
- Susan J. Lamont (Iowa State University)
Abstract
Gene expression changes after exposure to acute heatstress and/or to bacteriallipopolysaccharide (LPS) were investigated by measuring globalgene expression in two immune organs,bursa and thymus,from two chicken lines, Fayoumi and broiler. Over 1,600genes had significant expression changes in response to treatment; greaternumberswere identified in bursa for Fayoumi and in thymus forbroilers. Heat stress suppressed gene expression responses to LPS in both tissues.Both Heat and LPS impacted expression of immune cell traffickinggenes; these pathwaysneed to be investigated for potential to improve immune responses in heat-stressed chickens.
How to Cite:
Monson, M. S., Van Goor, A. G., Ashwell, C. M., Persia, M. E., Rothschild, M. F., Schmidt, C. J. & Lamont, S. J., (2017) “Exposure to Heat Stress and anImmune Stimulus AffectsGene Expression in Chicken Immune Tissues”, Iowa State University Animal Industry Report 14(1). doi: https://doi.org/10.31274/ans_air-180814-289
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