Textile and Apparel Science

Selective Detection of Gram-Negative Bacteria by Color Changing Polydiacetylene Nanofiber

  • Abhishek Bhattacharjee (Colorado State University)
  • Ketul C Popat (Colorado State University)
  • Yan Vivian Li (Colorado State University)


Pathogenic bacteria is one of the leading causes of human deaths around the world. Every year, millions of children and infants die due to severe bacterial diseases such as diarrhea which is mainly caused by Escherichia coli (E. coli) bacteria. To prevent high bacterial infection among humans, rapid and selective detection of bacteria is necessary. In this work, a polydiacetylene (PDA) nanofiber biosensor was prepared to selectively detect Gram-negative bacteria via a visible blue-to-red color change. The PDA fibers changed color when Gram-negative bacteria E. coli and Pseudomonas aeruginosa were tested, however, no color change was observed while testing with Gram-positive Staphylococcus aureus, thus confirming a selective detection of Gram-negative bacteria by the PDA fibers.

Keywords: Polydiacetylene, Nanofiber, Biosensor, Selective detection, Bacteria

How to Cite:

Bhattacharjee, A., Popat, K. C. & Li, Y. V., (2022) “Selective Detection of Gram-Negative Bacteria by Color Changing Polydiacetylene Nanofiber”, International Textile and Apparel Association Annual Conference Proceedings 79(1). doi: https://doi.org/10.31274/itaa.15958

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Published on
31 Dec 2022
Peer Reviewed