Breeding Physiology

Placement of Prolactin on Pig Chromosome 7 by Linkage and Physical Mapping

Authors: A. L. Vincent (Iowa State University) , L. Wang (Iowa State University) , Max F. Rothschild (Iowa State University)

Abstract

The study of genes which code for functional protein products have important implications in comparative genetic mapping and perhaps to the swine industry. The identification of a polymorphism, or change at the DNA level, is used to assign these genes to their corresponding chromosomes by the statistical method of two-point linkage analysis. A polymorphism was detected in the Prolactin gene (PRL) and was used to linkage map PRL to pig chromosome 7. To confirm this location, PRL also was genetically physically mapped using a pig x rodent somatic cell hybrid panel. These results confirm that the short arm of pig 7 contains another of the genes on human chromosome 6.

Keywords: ASL R1379

How to Cite: Vincent, A. L. , Wang, L. & Rothschild, M. F. (1997) “Placement of Prolactin on Pig Chromosome 7 by Linkage and Physical Mapping”, Iowa State University Animal Industry Report. 1(1).