Animal Health

Preparation of GP5-M Heterodimer Glycantype Specific Recombinant Protein and Replicon Particles

Authors: Ryan Vander Veen (Iowa State University) , Mark Mogler (Iowa State University) , Matthew M. Erdman (Iowa State University) , D.L. Hank Harris (Iowa State University)

Abstract

Porcine Reproductive and Respiratory Syndrome (PRRS) imposes a huge financial burden on the swine industry. Thus, there is a clear and immediate need for improved PRRS virus (PRRSV) vaccines. Our group has proposed a new classification scheme for PRRSV strains that allows for immunological differentiation based on level of GP5 glycosylation. This classification based on glycantype has allowed us to choose PRRSV strains that offer the best chance of protection against PRRS.

Keywords: ASL R2381

How to Cite: Vander Veen, R. , Mogler, M. , Erdman, M. M. & Harris, D. H. (2009) “Preparation of GP5-M Heterodimer Glycantype Specific Recombinant Protein and Replicon Particles”, Iowa State University Animal Industry Report. 6(1). doi: https://doi.org/10.31274/ans_air-180814-698